Artanis is an advisor to the Protoss player in Brood War and a high-ranking Protoss official. Artanis holds the rank of praetor in the Protoss Defense Forces, and at two hundred and sixty two years old, he is the youngest templar to achieve this rank. An ambitious leader, Artanis holds Tassadar in high esteem and despite being a strong believer in the Conclave the young Protoss also holds strongly to the idea of reunification with the dark templar. Initially appearing in Brood War, Artanis is voiced by Jack Ritschel and pilots a scout-class starfighter in-game. In the novel Queen of Blades, the player's actions in StarCraft's Episode III are ascribed to Artanis, which was later confirmed in an article released by Blizzard summarising the events of StarCraft.
Through Episode IV of Brood War, Artanis works with Zeratul and Judicator Aldaris to evacuate the Khalai Protoss to Shakuras and defend the world from the Zerg. During this time they receive unexpected aid from Sarah Kerrigan, but Artanis and Zeratul become furious at Kerrigan's true motives for being on Shakuras and her killing Aldaris. Despite knowing that destroying the Zerg and its cerebrates on Shakuras will only strengthen her, Artanis and Zeratul activate the Xel'Naga temple on Shakuras, annihilating the Zerg on the surface. Artanis does not appear again until the end of the game, in which he commands a fleet to bring Kerrigan to justice for the Protoss deaths she is responsible for, but his forces meet defeat despite outnumbering Kerrigan's standing forces. Returning to Shakuras and separated from Zeratul, Artanis and the Protoss survivors begin to rebuild their civilization. In the StarCraft 64 mission "Resurrection IV", Artanis enlists the aid of Jim Raynor to de-infest Alexei Stukov on Braxis, sterilizing the planet's surface afterwards.
At Blizzcon in August 2007 it was revealed that Artanis holds the rank of hierarch and thereby is effectively the leader of the reunified Protoss in StarCraft II, but is still struggling with reintegrating the two estranged branches of his people, as many of the Aiur survivors wish to retake their planet while the dark templar do not.